Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ACACB | O00763 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29673799 | 1.00 | KMT2A (0.61) | KMT2AACACBSMN1; SMN2NPC1MAPT | |
| SCHEMBL29673862 | 0.85 | SMN1; SMN2 (0.67) | KMT2ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL29673846 | 0.85 | SMN1; SMN2 (0.67) | KMT2ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL29673801 | 0.84 | ACACB (0.63) | KMT2AACACBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29673881 | 0.84 | ACACB (0.63) | KMT2AACACBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL12475741 | 0.81 | ACACB (0.86) | KMT2AACACBSMN1; SMN2NPC1MAPT | |
| SCHEMBL4519919 | 0.81 | MAPT (0.67) | KMT2AACACBSMN1; SMN2NPC1MAPT | |
| SCHEMBL26308661 | 0.80 | ACACB (0.54) | KMT2AACACBSMN1; SMN2NPC1MAPT | |
| SCHEMBL4949918 | 0.80 | KDM4E (0.64) | SMN1; SMN2NPC1MAPTRAB9ALMNA | |
| SCHEMBL5060920 | 0.80 | KDM4E (0.64) | SMN1; SMN2NPC1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685473-B | 5-Alkyl-2-pyrazole-oxazolidine-4-ketone derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-114685473-A | 5-alkyl-2-pyrazole-oxazolidine-4-ketone derivative and application thereof | 杭州百新生物医药科技有限公司 | 2022-07-01 | — | — | CN | disclosed |