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Ioglicic Acid

Ioglicic Acid

SCHEMBL29699760

CNC(=O)CNC(=O)c1c(I)c(NC(C)=O)c(I)c(C(=O)O)c1I

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ TSHR P16473 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ APEX1 P27695 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ioglicic Acid SCHEMBL667383 1.00 LMNA (0.55) LMNASMN1; SMN2TSHRMAPK1APEX1
SCHEMBL11697050 0.97 LMNA (0.52) LMNASMN1; SMN2TSHRMAPK1
SCHEMBL11694594 0.88 LMNA (0.41) LMNASMN1; SMN2TSHRMAPK1
SCHEMBL11700573 0.87 LMNA (0.58) LMNASMN1; SMN2TSHRMAPK1APEX1
SCHEMBL11694130 0.86 LMNA (0.52) LMNASMN1; SMN2TSHRMAPK1
SCHEMBL11775063 0.85 LMNA (0.51) LMNASMN1; SMN2TSHRMAPK1
SCHEMBL11775071 0.85 LMNA (0.51) LMNASMN1; SMN2TSHRMAPK1
SCHEMBL11695398 0.84 LMNA (0.56) LMNASMN1; SMN2TSHRMAPK1APEX1
SCHEMBL11695859 0.84 LMNA (0.48) LMNASMN1; SMN2TSHRMAPK1ALDH1A1
SCHEMBL11696569 0.84 LMNA (0.43) LMNASMN1; SMN2APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114867746-A Therapeutic antibodies against osteopontin 小利兰·斯坦福大学董事会 2022-08-05 — — CN disclosed
CN-114616250-A CD8 binding agents and uses thereof 豪夫迈·罗氏有限公司 2022-06-10 — — CN disclosed