SCHEMBL29699776

SCHEMBL29699776

Clc1ccc(Cl)c2cc3ccccc3cc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 8/20 0.58
CYP1A2 P05177 4/20 0.58
MAPT P10636 2/20 0.48
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43
NQO1 P15559 1/20 0.42
TSHR P16473 2/20 0.42
LMNA P02545 1/20 0.42
ALOX12 P18054 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
NQO2 P16083 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2816321 1.00 CYP2A6 (0.58) CYP2A6CYP1A2MAPTALDH1A1HSD17B10
SCHEMBL3240223 0.95 CYP2A6 (0.52) CYP2A6CYP1A2MAPTALDH1A1HSD17B10
SCHEMBL7913527 0.86 MAPT (0.48) CYP2A6CYP1A2MAPTALDH1A1HSD17B10
SCHEMBL476842 0.81 CYP2A6 (0.61) CYP2A6CYP1A2MAPTALDH1A1HSD17B10
SCHEMBL29520686 0.81 CYP2A6 (0.61) CYP2A6CYP1A2MAPTALDH1A1HSD17B10
SCHEMBL28321692 0.81 KMT2A (0.47) CYP2A6CYP1A2MAPTALDH1A1HSD17B10
SCHEMBL1310983 0.79 CYP2A6 (0.58) CYP2A6CYP1A2MAPTALDH1A1HSD17B10
SCHEMBL6036927 0.79 CYP2A6 (0.58) CYP2A6CYP1A2MAPTALDH1A1HSD17B10
SCHEMBL9617601 0.79 CYP2A6 (0.48) CYP2A6CYP1A2MAPTALDH1A1HSD17B10
SCHEMBL8476508 0.79 CYP2A6 (0.58) CYP2A6CYP1A2MAPTALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116116205-A Method for retarding generation of chloro-and bromo-polycyclic aromatic hydrocarbon by polycyclic aromatic hydrocarbon precursor 国科大杭州高等研究院 2023-05-16 CN disclosed
CN-111302961-B Method for synthesizing N-aryl/alkyl anthraquinone and derivatives thereof under catalysis of carbene metal ligand 中国科学院兰州化学物理研究所 2022-06-14 CN disclosed