SCHEMBL9617601

SCHEMBL9617601

Clc1ccc(Cl)c2c(Cl)c3cc4ccccc4cc3c(Cl)c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.48
MAPT P10636 2/20 0.42
CYP1A2 P05177 2/20 0.42
ALDH1A1 P00352 3/20 0.37
HIF1A Q16665 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP1B1 Q16678 1/20 0.37
NQO1 P15559 1/20 0.37
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
ITGB2 P05107 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31518688 0.82 CYP2A6 (0.50) CYP2A6MAPTCYP1A2ALDH1A1HIF1A
SCHEMBL15757917 0.82 CYP2A6 (0.50) CYP2A6MAPTCYP1A2ALDH1A1HIF1A
SCHEMBL4369821 0.81 CYP2A6 (0.41) CYP2A6MAPTCYP1A2ALDH1A1HIF1A
SCHEMBL7918983 0.79 CYP2A6 (0.48) CYP2A6MAPTCYP1A2ALDH1A1HIF1A
SCHEMBL2816321 0.79 CYP2A6 (0.58) CYP2A6MAPTCYP1A2ALDH1A1HIF1A
SCHEMBL29699776 0.79 CYP2A6 (0.58) CYP2A6MAPTCYP1A2ALDH1A1HIF1A
SCHEMBL3242358 0.77 MAOA (0.50) CYP2A6MAPTCYP1A2ALDH1A1HIF1A
SCHEMBL30843834 0.77 MAOA (0.50) CYP2A6MAPTCYP1A2ALDH1A1HIF1A
SCHEMBL3216540 0.75 CYP2A6 (0.44) CYP2A6MAPTCYP1A2ALDH1A1HIF1A
SCHEMBL9550562 0.75 CYP2A6 (0.44) CYP2A6MAPTCYP1A2ALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4049274-A None JP disclosed
JP-H0449274-A NOVEL TETRASELENOTETRACENE AND COMPLEX CONTAINING THE SAME DAISO CO LTD 1992-02-18 JP disclosed