Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16347172 | 0.87 | CYP19A1 (0.54) | CYP19A1PTGER1CYP1A2L3MBTL1PTGDR2 | |
| SCHEMBL29699741 | 0.86 | CYP19A1 (0.53) | CYP19A1PTGER1CYP1A2L3MBTL1PTGDR2 | |
| SCHEMBL29699825 | 0.86 | CYP19A1 (0.53) | CYP19A1PTGER1CYP1A2L3MBTL1PTGDR2 | |
| SCHEMBL29699923 | 0.86 | CYP19A1 (0.64) | CYP19A1PTGER1L3MBTL1PTGDR2SMN1; SMN2 | |
| SCHEMBL29699814 | 0.86 | MEN1 (0.61) | CYP19A1PTGER1CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL1233306 | 0.86 | SMN1; SMN2 (0.60) | CYP19A1PTGER1CYP1A2SMN1; SMN2KMT2A | |
| SCHEMBL16347525 | 0.85 | CYP19A1 (0.53) | CYP19A1PTGER1CYP1A2L3MBTL1PTGDR2 | |
| Bicarbonate SCHEMBL2360581 | 0.85 | SMN1; SMN2 (0.58) | CYP19A1PTGER1CYP1A2SMN1; SMN2KMT2A | |
| SCHEMBL29699803 | 0.85 | PTGER1 (0.69) | PTGER1CYP1A2PTGDR2KMT2AMEN1 | |
| SCHEMBL2360580 | 0.84 | SMN1; SMN2 (0.47) | PTGER1CYP1A2SMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685371-A | Pyrazole carboxamide derivatives, their preparation and use | 四川大学 | 2022-07-01 | — | — | CN | disclosed |