Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 16/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137143 | 0.86 | PTGER1 (0.59) | PTGER1CYP1A2MEN1KMT2AP2RY14 | |
| SCHEMBL29699784 | 0.85 | CYP19A1 (0.57) | PTGER1CYP1A2PTGDR2MEN1KMT2A | |
| SCHEMBL29699870 | 0.85 | MEN1 (0.67) | PTGER1CYP1A2MEN1KMT2A | |
| SCHEMBL29700093 | 0.84 | MEN1 (0.67) | PTGER1CYP1A2MEN1KMT2AP2RY14 | |
| SCHEMBL18295022 | 0.84 | PTGER1 (0.64) | PTGER1CYP1A2P2RY14 | |
| SCHEMBL29700069 | 0.83 | PTGER1 (0.51) | PTGER1CYP1A2PTGDR2MEN1KMT2A | |
| SCHEMBL29699906 | 0.83 | MARS1 (0.57) | PTGER1CYP1A2PTGDR2MEN1KMT2A | |
| SCHEMBL4681451 | 0.82 | PTGER1 (1.00) | PTGER1CYP1A2 | |
| SCHEMBL29699759 | 0.81 | MEN1 (0.79) | PTGER1MEN1KMT2AP2RY14 | |
| SCHEMBL29699847 | 0.79 | MEN1 (0.66) | PTGER1MEN1KMT2AP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685371-A | Pyrazole carboxamide derivatives, their preparation and use | 四川大学 | 2022-07-01 | — | — | CN | disclosed |