Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 10/20 | 0.59 |
| ▸ | ERN1 | O75460 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18397589 | 1.00 | POLB (0.60) | POLBHPGDERN1TSHRSMN1; SMN2 | |
| SCHEMBL29700141 | 0.88 | POLB (0.64) | POLBHPGDERN1TSHRSMN1; SMN2 | |
| SCHEMBL18397586 | 0.88 | POLB (0.64) | POLBHPGDERN1TSHRSMN1; SMN2 | |
| SCHEMBL18407724 | 0.86 | HPGD (0.60) | POLBHPGDERN1TSHRSMN1; SMN2 | |
| SCHEMBL18397590 | 0.86 | CYP3A4 (0.49) | POLBHPGDERN1TSHRSMN1; SMN2 | |
| SCHEMBL29699917 | 0.86 | CYP3A4 (0.49) | POLBHPGDERN1TSHRSMN1; SMN2 | |
| SCHEMBL19088580 | 0.84 | HPGD (0.68) | POLBHPGDTSHRSMN1; SMN2LMNA | |
| SCHEMBL18397576 | 0.83 | HPGD (0.70) | POLBHPGDERN1SMN1; SMN2LMNA | |
| SCHEMBL12183401 | 0.83 | HPGD (0.67) | POLBHPGDTSHRSMN1; SMN2LMNA | |
| SCHEMBL18407780 | 0.80 | HSD17B10 (0.65) | HPGDTSHRSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646207-A1 | COMPOSITIONS FOR HORMONALLY IMPACTED SKIN | The Boots Company PLC (GB) | 2025-11-12 | — | — | EP | claimed |
| WO-2024146870-A1 | COMPOSITIONS FOR HORMONALLY IMPACTED SKIN | THE BOOTS COMPANY PLC (GB) | 2024-07-11 | — | — | WO | claimed |
| WO-2024146869-A1 | COMPOSITIONS FOR HORMONALLY IMPACTED SKIN | THE BOOTS COMPANY PLC (GB) | 2024-07-11 | — | — | WO | claimed |
| CN-114615969-B | New method | 帝斯曼知识产权资产管理有限公司 | 2024-01-23 | — | — | CN | claimed |
| EP-4054575-A1 | NOVEL METHOD | DSM IP Assets B.V. (NL) | 2022-09-14 | — | — | EP | claimed |
| CN-114615969-A | Novel process | 帝斯曼知识产权资产管理有限公司 | 2022-06-10 | — | — | CN | claimed |
| EP-4646207-A1 | COMPOSITIONS FOR HORMONALLY IMPACTED SKIN | The Boots Company PLC (GB) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024146868-A1 | COMPOSITIONS FOR HORMONALLY IMPACTED SKIN | THE BOOTS COMPANY PLC (GB) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024146869-A1 | COMPOSITIONS FOR HORMONALLY IMPACTED SKIN | THE BOOTS COMPANY PLC (GB) | 2024-07-11 | — | — | WO | disclosed |