Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 10/20 | 0.64 |
| ▸ | ERN1 | O75460 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18397586 | 1.00 | POLB (0.64) | POLBHPGDERN1TSHRMEN1 | |
| SCHEMBL18397589 | 0.88 | POLB (0.60) | POLBHPGDERN1TSHRMEN1 | |
| SCHEMBL29699889 | 0.88 | POLB (0.60) | POLBHPGDERN1TSHRMEN1 | |
| SCHEMBL18397576 | 0.87 | HPGD (0.70) | POLBHPGDERN1MEN1ALDH1A1 | |
| SCHEMBL23440313 | 0.83 | HPGD (0.71) | POLBHPGDERN1MEN1ALDH1A1 | |
| SCHEMBL18397598 | 0.83 | HPGD (0.71) | POLBHPGDERN1MEN1ALDH1A1 | |
| SCHEMBL29699833 | 0.83 | HPGD (0.71) | POLBHPGDERN1MEN1ALDH1A1 | |
| SCHEMBL17689127 | 0.83 | HPGD (0.73) | POLBHPGDTSHRALDH1A1KMT2A | |
| SCHEMBL18397573 | 0.82 | HPGD (0.74) | POLBHPGDERN1MEN1ALDH1A1 | |
| SCHEMBL28504587 | 0.82 | HPGD (0.72) | POLBHPGDERN1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114615969-B | New method | 帝斯曼知识产权资产管理有限公司 | 2024-01-23 | — | — | CN | claimed |
| EP-4054575-A1 | NOVEL METHOD | DSM IP Assets B.V. (NL) | 2022-09-14 | — | — | EP | claimed |
| CN-114615969-A | Novel process | 帝斯曼知识产权资产管理有限公司 | 2022-06-10 | — | — | CN | claimed |