Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 3/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.60 |
| ▸ | CLK1 | P49759 | 2/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15903807 | 0.78 | TDO2 (0.56) | CDK5CDK5R1CLK1GSK3BDYRK1A | |
| SCHEMBL29488162 | 0.75 | GSK3B (1.00) | CDK5CDK5R1CLK1GSK3BDYRK1A | |
| SCHEMBL573402 | 0.75 | GSK3B (1.00) | CDK5CDK5R1CLK1GSK3BDYRK1A | |
| SCHEMBL28228155 | 0.74 | HSD17B10 (0.59) | CDK5CDK5R1CLK1GSK3BDYRK1A | |
| SCHEMBL20030496 | 0.74 | DYRK1A (0.72) | CDK5CDK5R1CLK1GSK3BDYRK1A | |
| SCHEMBL28399449 | 0.74 | MEN1 (0.65) | CDK5CDK5R1CLK1GSK3BDYRK1A | |
| SCHEMBL28228733 | 0.73 | PI4KA (0.47) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17179419 | 0.72 | PDGFRB (0.62) | CDK5CDK5R1CLK1GSK3BDYRK1A | |
| SCHEMBL24839575 | 0.72 | CLK1 (0.71) | CDK5CDK5R1CLK1GSK3BDYRK1A | |
| SCHEMBL16075920 | 0.72 | CLK1 (0.71) | CDK5CDK5R1CLK1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12258344-B2 | Azaaromatic amide derivatives for the treatment of cancer | SHENZHEN FORWARD PHARMACEUTICALS CO., LTD. (CN) | 2025-03-25 | — | — | US | disclosed |
| US-20220177473-A1 | AZAAROMATIC AMIDE DERIVATIVES FOR THE TREATMENT OF CANCER | SHENZHEN FORWARD PHARMACEUTICALS CO., LTD. (CN) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177473-A1 | AZAAROMATIC AMIDE DERIVATIVES FOR THE TREATMENT OF CANCER | ERBB4, EGFR, ERBB2 | CDK5 608/4885CDK5R1 1001/4885CLK1 4489/4885 |
| US-12258344-B2 | Azaaromatic amide derivatives for the treatment of cancer | ERBB4, EGFR, ERBB2 | CDK5 608/4885CDK5R1 1001/4885CLK1 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.