Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23121198 | 1.00 | LMNA (0.68) | LMNAL3MBTL1CYP11B1ALDH1A1POLB | |
| SCHEMBL31270697 | 0.82 | LMNA (0.74) | LMNAL3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL17102309 | 0.81 | LMNA (0.64) | LMNAL3MBTL1CYP11B1ALDH1A1POLB | |
| SCHEMBL169675 | 0.78 | LMNA (0.68) | LMNAL3MBTL1CYP11B1ALDH1A1POLB | |
| SCHEMBL31729500 | 0.78 | LMNA (0.68) | LMNAL3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL26127200 | 0.76 | LMNA (0.54) | LMNAL3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL2950629 | 0.76 | LMNA (0.71) | LMNAL3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL301107 | 0.76 | LMNA (0.66) | LMNAL3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL22180828 | 0.75 | LMNA (0.60) | LMNAL3MBTL1CYP11B1ALDH1A1CHRNB2 | |
| SCHEMBL277927 | 0.75 | LMNA (0.64) | LMNAL3MBTL1CYP11B1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031240-A1 | NEW COMPOUNDS | Vicore Pharma AB (SE) | 2022-07-27 | — | — | EP | disclosed |
| CN-114786774-A | Novel compounds | 维科尔药物公司 | 2022-07-22 | — | — | CN | disclosed |