Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 1.00 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.68 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.68 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | MTOR | P42345 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | HTR2C | P28335 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679320 | 1.00 | SLC6A4 (1.00) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL7317614 | 0.94 | SLC6A4 (0.88) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL17267556 | 0.91 | SLC6A4 (0.83) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL17267540 | 0.90 | SLC6A4 (0.81) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL5570738 | 0.89 | SLC6A4 (0.81) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL8971141 | 0.89 | SLC6A4 (0.81) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL10076387 | 0.88 | SLC6A4 (0.79) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL7943264 | 0.88 | SLC6A4 (0.79) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL11925287 | 0.88 | SLC6A4 (0.79) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL3415108 | 0.88 | SLC6A4 (0.78) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736134-B | (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof | 浙江工业大学台州研究院 | 2023-06-06 | — | — | CN | disclosed |
| CN-114736134-A | (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof | 浙江工业大学台州研究院 | 2022-07-12 | — | — | CN | disclosed |