Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 1.00 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.68 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.68 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | MTOR | P42345 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | HTR2C | P28335 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29700710 | 1.00 | SLC6A4 (1.00) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL7317614 | 0.94 | SLC6A4 (0.88) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL17267556 | 0.91 | SLC6A4 (0.83) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL17267540 | 0.90 | SLC6A4 (0.81) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL5570738 | 0.89 | SLC6A4 (0.81) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL8971141 | 0.89 | SLC6A4 (0.81) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL10076387 | 0.88 | SLC6A4 (0.79) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL7943264 | 0.88 | SLC6A4 (0.79) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL11925287 | 0.88 | SLC6A4 (0.79) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL3415108 | 0.88 | SLC6A4 (0.78) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270483-A1 | PROCESS FOR THE PREPARATION OF ARYLOXYPROPYLAMINES | DIPHARMA FRANCIS S.R.L. (IT) | 2007-11-22 | — | — | US | claimed |
| EP-1857435-A2 | A process for the preparation of aryloxypropylamines | Dipharma Francis S.r.l. (IT) | 2007-11-21 | — | — | EP | claimed |
| WO-2000021917-A1 | PHARMACEUTICAL INTERMEDIATE FOR THE SYNTHESIS OF FLUOXETINE AND A PROCESS FOR THE PREPARATION THEREOF | EGIS Gyógyszergyár Rt. (HU) | 2000-04-20 | — | — | WO | claimed |
| EP-0929514-A1 | PROCESS FOR THE PREPARATION OF FLUOXETINE | EGIS GYOGYSZERGYAR RT. (HU) | 1999-07-21 | — | — | EP | claimed |
| WO-1998011054-A1 | PROCESS FOR THE PREPARATION OF FLUOXETINE | EGIS Gyógyszergyár Rt. (HU) | 1998-03-19 | — | — | WO | claimed |
| US-4584404-A | ANTIDEPRESSANT | ELI LILLY AND COMPANY (US) | 1986-04-22 | — | — | US | claimed |
| CN-114736134-B | (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof | 浙江工业大学台州研究院 | 2023-06-06 | — | — | CN | disclosed |
| CN-114736134-A | (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof | 浙江工业大学台州研究院 | 2022-07-12 | — | — | CN | disclosed |
| US-20220202808-A1 | Compositions For Affecting Weight Loss | NALPROPION PHARMACEUTICALS LLC (US) | 2022-06-30 | — | — | US | disclosed |
| EP-3281628-B1 | COMPOSITIONS FOR AFFECTING WEIGHT LOSS | NALPROPION PHARMACEUTICALS INC (US) | 2019-09-11 | — | — | EP | disclosed |
| EP-3281628-B1 | COMPOSITIONS FOR AFFECTING WEIGHT LOSS | NALPROPION PHARMACEUTICALS INC (US) | 2019-09-11 | — | — | EP | disclosed |
| US-20190216799-A1 | Compositions For Affecting Weight Loss | WILMINGTON SAVINGS FUND SOCIETY, FSB | 2019-07-18 | — | — | US | disclosed |
| US-10238647-B2 | Compositions for affecting weight loss | NALPROPION PHARMACEUTICALS, INC. (US) | 2019-03-26 | — | — | US | disclosed |
| US-5166437-A | Process for the preparation of fluoxetine | ORION-YHTYMA OY (FI) | 1992-11-24 | — | — | US | disclosed |
| EP-0391070-A1 | Process for the preparation of N-methyl-3-(p-trifluoro-methylphenoxy)-3-phenyl-propylamine and their salts | ORION-YHTYMÄ OY FERMION (FI) | 1990-10-10 | — | — | EP | disclosed |
| US-4626549-A | Treatment of obesity with aryloxyphenylpropylamines | ELI LILLY AND COMPANY (US) | 1986-12-02 | — | — | US | disclosed |
| US-4584404-A | ANTIDEPRESSANT | ELI LILLY AND COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| US-4314081-A | ANTIDEPRESSANTS | ELI LILLY AND COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4194009-A | ANTIDEPRESSANT | ELI LILLY AND COMPANY (US) | 1980-03-18 | — | — | US | disclosed |
| US-4018895-A | Aryloxyphenylpropylamines in treating depression | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202808-A1 | Compositions For Affecting Weight Loss | MC4R, MC3R, MC5R | SLC6A4 978/4885HRH3 555/4885SLC6A9 4130/4885 |
| US-10238647-B2 | Compositions for affecting weight loss | MC4R, MC3R, MC5R | SLC6A4 978/4885HRH3 555/4885SLC6A9 4130/4885 |
| US-20070270483-A1 | PROCESS FOR THE PREPARATION OF ARYLOXYPROPYLAMINES | NAT1, C1S, PAH | SLC6A4 310/4885HRH3 12/4885SLC6A9 221/4885 |
| US-20190216799-A1 | Compositions For Affecting Weight Loss | MC4R, MC3R, MC5R | SLC6A4 978/4885HRH3 555/4885SLC6A9 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.