Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.62 |
| ▸ | ITGAV | P06756 | 20/20 | 0.62 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.59 |
| ▸ | ITGB6 | P18564 | 9/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.56 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.56 |
| ▸ | ITGB8 | P26012 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140807 | 1.00 | ITGB3 (0.62) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL20140803 | 1.00 | ITGB3 (0.62) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL21317545 | 1.00 | ITGB3 (0.62) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL20158050 | 1.00 | ITGB3 (0.62) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL20158219 | 0.94 | ITGB3 (0.61) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL20142087 | 0.92 | ITGB3 (0.58) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL20142092 | 0.92 | ITGB3 (0.58) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL29701353 | 0.92 | ITGB3 (0.58) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL21314351 | 0.91 | ITGAV (0.61) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL21317480 | 0.91 | ITGAV (0.61) | ITGB3ITGAVITGB5ITGA2BITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167934-B | Cyclobutane-and azetidine-containing monocyclic and spiro compounds as alpha V integrin inhibitors | 百时美施贵宝公司 | 2022-06-10 | — | — | CN | claimed |