Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 18/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.43 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.41 |
| ▸ | ITGB8 | P26012 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487505 | 1.00 | ITGAV (0.47) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL20158103 | 1.00 | ITGAV (0.47) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL20141446 | 0.91 | ITGAV (0.54) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL20141445 | 0.91 | ITGAV (0.54) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL20158101 | 0.85 | ITGAV (0.60) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL30487535 | 0.85 | ITGAV (0.60) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL20158099 | 0.80 | CHRNA7 (0.37) | ITGAVITGB3ITGA2BITGB5ITGB1 | |
| SCHEMBL30487514 | 0.80 | CHRNA7 (0.37) | ITGAVITGB3ITGA2BITGB5ITGB1 | |
| SCHEMBL21317544 | 0.79 | CHRNA7 (0.36) | ITGAVITGB3 | |
| SCHEMBL20141277 | 0.76 | ITGAV (0.70) | ITGAVITGB3ITGA2BITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167934-B | Cyclobutane-and azetidine-containing monocyclic and spiro compounds as alpha V integrin inhibitors | 百时美施贵宝公司 | 2022-06-10 | — | — | CN | disclosed |