Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 8/20 | 0.40 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16607425 | 1.00 | ITGAV (0.40) | ITGAVITGB6ITGB3ITGA2BMPO | |
| SCHEMBL22223394 | 0.97 | ITGAV (0.40) | ITGAVITGB6ITGB3ITGA2BMPO | |
| SCHEMBL30474548 | 0.97 | ITGAV (0.40) | ITGAVITGB6ITGB3ITGA2BMPO | |
| SCHEMBL16607380 | 0.96 | ITGAV (0.40) | ITGAVITGB6ITGB3ITGA2BMPO | |
| Lithium SCHEMBL30471754 | 0.96 | ITGAV (0.40) | ITGAVITGB6ITGB3ITGA2BMPO | |
| SCHEMBL29390935 | 0.94 | MPO (0.39) | ITGAVITGB6ITGB3MPOGPR119 | |
| SCHEMBL3138861 | 0.94 | MPO (0.39) | ITGAVITGB6ITGB3MPOGPR119 | |
| SCHEMBL17970755 | 0.93 | MPO (0.39) | ITGAVITGB6MPOGPR119ESR2 | |
| SCHEMBL24908851 | 0.89 | MPO (0.39) | ITGAVITGB6MPOGPR119ESR2 | |
| SCHEMBL19953719 | 0.89 | MPO (0.39) | ITGAVITGB6MPOGPR119ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024260259-A1 | INTEGRIN LIGAND AND USE THEREOF | 广东众生睿创生物科技有限公司 | 2024-12-26 | — | — | WO | disclosed |
| CN-110167934-B | Cyclobutane-and azetidine-containing monocyclic and spiro compounds as alpha V integrin inhibitors | 百时美施贵宝公司 | 2022-06-10 | — | — | CN | disclosed |