SCHEMBL297024

SCHEMBL297024

Cc1cc(C2(c3cc(C)c(O)c(Br)c3)CC(C)CC(C)(C)C2)cc(Br)c1O

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.54
ESR2 Q92731 1/20 0.54
ACHE P22303 1/20 0.38
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6261075 0.91 ESR1 (0.46) ESR1ESR2ACHE
SCHEMBL296906 0.91 ESR1 (0.59) ESR1ESR2
SCHEMBL298066 0.90 ESR1 (0.61) ESR1ESR2ACHE
SCHEMBL6264020 0.85 ESR1 (0.41) ESR1ESR2
SCHEMBL299026 0.83 ESR1 (0.54) ESR1ESR2ACHEMAOA
SCHEMBL297177 0.82 ESR1 (0.50) ESR1ESR2
SCHEMBL297898 0.82 ESR1 (0.50) ESR1ESR2
SCHEMBL7065992 0.81 ESR1 (0.51) ESR1ESR2ACHE
SCHEMBL2779179 0.81 ESR1 (0.51) ESR1ESR2ACHEMAOA
SCHEMBL7064600 0.81 ESR1 (0.51) ESR1ESR2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-11898025-B2 Polyethylene with additives for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-02-13 US disclosed
US-11535732-B2 Polyethylene with polycarbonate-siloxane for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-12-27 US disclosed
US-20210388189-A1 POLYETHYLENE WITH ADDITIVES FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-16 US disclosed
US-20210309839-A1 POLYETHYLENE WITH POLYCARBONATE-SILOXANE FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-10-07 US disclosed
EP-3877463-A1 POLYETHYLENE WITH ADDITIVES FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC Global Technologies B.V. (NL) 2021-09-15 EP disclosed
EP-3802687-A1 POLYETHYLENE WITH POLYCARBONATE-SILOXANE FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC Global Technologies B.V. (NL) 2021-04-14 EP disclosed
US-10654973-B2 Method for producing polycarbonate SHELL OIL COMPANY (US) 2020-05-19 US disclosed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US disclosed
US-20030149223-A1 Method of polycarbonate preparation GENERAL ELECTRIC COMPANY 2003-08-07 US disclosed
US-6548623-B2 Melt reaction of bisphenol A and bis-methyl salicyl carbonate using alkali or alkaline earth metal catalyst and quaternary ammonium or phosphonium compound; Fries suppression; by-product inhibition GENERAL ELECTRIC COMPANY 2003-04-15 US disclosed
US-20030050427-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY 2003-03-13 US disclosed
US-6518391-B1 Method of polycarbonate preparation by solid state polymerization GENERAL ELECTRIC COMPANY 2003-02-11 US disclosed
WO-2003010219-A1 METHOD OF POLYCARBONATE PREPARATION BY SOLID STATE POLYMERIZATION GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed
US-6506871-B1 Ester interchange of bis(methyl salicyl) carbonate and bisphenol A in presence of tetrabutylphosphonium acetate catalyst GENERAL ELECTRIC COMPANY 2003-01-14 US disclosed
US-6420512-B1 SCREW EXTRUSION AND ESTER INTERCHANGE GENERAL ELECTRIC COMPANY 2002-07-16 US disclosed