SCHEMBL296906

SCHEMBL296906

CC1CC(C)(C)CC(c2cc(Br)c(O)c(Br)c2)(c2cc(Br)c(O)c(Br)c2)C1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.59
ESR2 Q92731 1/20 0.59
CYP3A4 P08684 2/20 0.32
TSHR P16473 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
CASP1 P29466 1/20 0.32
RECQL P46063 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297024 0.91 ESR1 (0.54) ESR1ESR2
SCHEMBL297898 0.87 ESR1 (0.50) ESR1ESR2
SCHEMBL297177 0.87 ESR1 (0.50) ESR1ESR2ALDH1A1
SCHEMBL296665 0.84 ESR1 (0.50) ESR1ESR2CYP3A4TSHRTDP1
SCHEMBL30295754 0.83 ESR1 (0.63) ESR1ESR2TSHRALDH1A1ALOX15
SCHEMBL296382 0.83 ESR1 (0.63) ESR1ESR2TSHRALDH1A1ALOX15
SCHEMBL6261075 0.83 ESR1 (0.46) ESR1ESR2
SCHEMBL298066 0.82 ESR1 (0.61) ESR1ESR2
SCHEMBL20702059 0.81 ESR1 (0.44) ESR1ESR2
SCHEMBL7916374 0.81 ESR1 (0.59) ESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1560871-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-08-10 EP claimed
WO-2004041907-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-05-21 WO claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
US-20240101859-A1 RESIN COMPOSITION FOR COATING, POLYMER, METHOD FOR PRODUCING POLYMER, COATING FILM, AND METHOD FOR MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2024-03-28 US disclosed
US-20240092967-A1 RESIN COMPOSITION FOR COATING, POLYMER, METHOD FOR PRODUCING POLYMER, COATING FILM, AND METHOD FOR MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2024-03-21 US disclosed
EP-4339251-A1 COATING RESIN COMPOSITION, POLYMER, POLYMER PRODUCTION METHOD, COATING FILM AND PRODUCTION METHOD THEREFOR FUJIFILM Corporation (JP) 2024-03-20 EP disclosed
EP-4339252-A1 RESIN COMPOSITION FOR COATING, POLYMER, METHOD FOR PRODUCING POLYMER, COATING FILM AND METHOD FOR PRODUCING SAME FUJIFILM Corporation (JP) 2024-03-20 EP disclosed
US-11936103-B2 Conductive film for antennas, and antenna TEIJIN LIMITED (JP) 2024-03-19 US disclosed
US-5512632-A MOLDING MATERIAL BAYER AKTIENGESELLSCHAFT (DE) 1996-04-30 US disclosed
EP-0691201-A2 Spray-coated laminats with colour layer BAYER AG (DE) 1996-01-10 EP disclosed
EP-0443058-A1 Polyesters and polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes BAYER AG (DE) 1991-08-28 EP disclosed
US-5041521-A High impact strength, stress releiving, noncracking BAYER AKTIENGESELLSCHAFT (DE) 1991-08-20 US disclosed
EP-0419926-A1 Thermoplastic alloys with polyesters and polyestercarbonates based on substituted cycloalkylidenebisphenols BAYER AG (DE) 1991-04-03 EP disclosed