SCHEMBL297029

SCHEMBL297029

Nc1ccc([N+](=O)[O-])c2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.61
CTSB P07858 4/20 0.60
ALDH1A1 P00352 5/20 0.53
AR P10275 1/20 0.50
TSHR P16473 3/20 0.48
CYP3A4 P08684 2/20 0.48
ALOX15 P16050 2/20 0.48
MEN1 O00255 1/20 0.48
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48
KMT2A Q03164 1/20 0.48
PDE7A Q13946 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HPRT1 P00492 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6815901 1.00 TDP1 (0.61) TDP1CTSBALDH1A1ARTSHR
SCHEMBL31689625 0.88 TDP1 (0.75) TDP1CTSBALDH1A1TSHRCYP3A4
SCHEMBL31689391 0.88 TDP1 (0.75) TDP1CTSBALDH1A1TSHRCYP3A4
SCHEMBL1126918 0.88 TDP1 (0.75) TDP1CTSBALDH1A1TSHRCYP3A4
SCHEMBL7788656 0.87 TDP1 (0.80) TDP1CTSBALDH1A1ARTSHR
Hydrochloric Acid SCHEMBL4657730 0.86 TDP1 (0.72) TDP1CTSBALDH1A1TSHRCYP3A4
SCHEMBL11044835 0.84 TDP1 (0.68) TDP1CTSBALDH1A1TSHRCYP3A4
SCHEMBL11436046 0.81 ALDH1A1 (0.52) TDP1CTSBALDH1A1TSHRCYP3A4
SCHEMBL11818622 0.80 ALDH1A1 (0.61) TDP1CTSBALDH1A1TSHRCYP3A4
SCHEMBL8689065 0.80 TDP1 (0.57) TDP1CTSBALDH1A1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116751162-B Quinoline compound, preparation method thereof, pharmaceutical composition and medical application 中国人民解放军军事科学院军事医学研究院 2025-02-28 CN claimed
CN-118004997-A Preparation method of pore-diameter-adjustable porous carbon material 东南大学 2024-05-10 CN claimed
CN-117623996-A Bivalent KEAP1-NRF2 inhibitor, preparation method and medical application thereof 中国药科大学 2024-03-01 CN claimed
CN-116751162-A Quinoline compound, preparation method thereof, pharmaceutical composition and medical application 中国人民解放军军事科学院军事医学研究院 2023-09-15 CN claimed
CN-108640919-B Matrine derivative and sophoridine derivative containing aryl amidine or aminoquinoline structure and preparation method thereof 广西大学 2020-09-08 CN claimed
CN-109134971-B Functional zirconium phosphate modified anti-aging nitrile rubber composite material and preparation method thereof 西南石油大学 2020-08-07 CN claimed
US-9611502-B2 Method for simultaneously measuring activity of various enzymes by using multi-wavelength absorption single channel CHONGQING MEDICAL UNIVERSITY (CN) 2017-04-04 US claimed
US-20150225764-A1 METHOD FOR SIMULTANEOUSLY MEASURING ACTIVITY OF VARIOUS ENZYMES BY USING MULTI-WAVELENGTH ABSORPTION SINGLE CHANNEL CHONGQING MEDICAL UNIVERSITY (CN) 2015-08-13 US claimed
US-9085715-B2 Process for assembling two surfaces or one surface with a molecule of interest COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2015-07-21 US claimed
CN-102046744-B Method for assembling two surfaces, or one surface, with a molecule of interest COMMISSARIAT ENERGIE ATOMIQUE 2015-07-15 CN claimed
EP-2285923-A2 METHOD FOR ASSEMBLING TWO SURFACES, OR ONE SURFACE, WITH A MOLECULE OF INTEREST Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2011-02-23 EP claimed
WO-2011017317-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-02-10 WO claimed
US-20090286308-A1 Process for assembling two surfaces or one surface with a molecule of interest COMMISSARIAT A L' ENERGIE ATOMIQUE 2009-11-19 US claimed
WO-2009121944-A2 METHOD FOR ASSEMBLING TWO SURFACES, OR ONE SURFACE, WITH A MOLECULE OF INTEREST COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2009-10-08 WO claimed
EP-0337698-B1 Photosensitive Polymer CHISSO CORP (JP) 1993-11-10 EP claimed
EP-0337698-A2 Photosensitive Polymer Chisso Corporation (JP) 1989-10-18 EP claimed
US-4657993-A PREPARED FROM DICHLOROPHOSPHAZENES CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1987-04-14 US claimed
EP-0200854-A2 Phosphazene homopolymers and copolymers having hydroxylated or amino derivatives of carbazole or of naphthalene as substituents CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1986-12-17 EP claimed
US-4321319-A Photosensitive compositions containing polyamides acid with photosensitive groups HITACHI, LTD. (JP) 1982-03-23 US claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed