SCHEMBL297033

SCHEMBL297033

CON=C(C(=O)OC)c1ccccc1CON=C(C)c1cccc(C(F)(F)F)c1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.64
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
RXFP1 Q9HBX9 2/20 0.41
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28465127 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL4448910 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL19148 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL29368184 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL9880011 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL2321633 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL29363702 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL7960472 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL12635931 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
Hydrochloric Acid SCHEMBL17701148 0.99 HIF1A (0.63) HIF1AMEN1KMT2APPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252719-B2 Microemulsifiable hydrophobic concentrates containing an alkyl alkanoate with a poyhydric alcohol, a polyhydric alcohol condensate or a mixture thereof and at least one surfactant; nontoxic, preemergent and postemergent herbicides; improved storage stability SYNGENTA LIMITED (GB) 2012-08-28 US claimed
US-20050043182-A1 Agrochemical compositions SYNGENTA CROP PROTECTION, INC. 2005-02-24 US claimed
US-20030130290-A1 Fungicidal combinations comprising thieno[2,3-d]pyrimidin-4-one MULLER KASPAR (CH) 2003-07-10 US claimed
US-20030065001-A1 Fungicidal combinations comprising quinazolinone WALTER HARALD (CH) 2003-04-03 US claimed
US-20020035038-A1 Fungicidal combinations comprising thieno[2,3-d]pyrimidin-4-one WALTER HARALD (CH) 2002-03-21 US claimed
EP-1124422-A1 FUNGICIDAL COMBINATIONS COMPRISING THIENO[2,3-d]PYRIMIDIN-4-ONE Syngenta Participations AG (CH) 2001-08-22 EP claimed
EP-1035773-A1 FUNGICIDAL COMBINATIONS COMPRISING THIENO 2,3-d]PYRIMIDIN-4-ONE Novartis AG (CH) 2000-09-20 EP claimed
EP-1035774-A1 FUNGICIDAL COMBINATIONS COMPRISING QUINAZOLINONE Novartis AG (CH) 2000-09-20 EP claimed
WO-2000027200-A1 FUNGICIDAL COMBINATIONS COMPRISING THIENO[2,3-d]PYRIMIDIN-4-ONE SYNGENTA PARTICIPATIONS AG (CH) 2000-05-18 WO claimed
WO-1999027790-A1 FUNGICIDAL COMBINATIONS COMPRISING THIENO[2,3-d]PYRIMIDIN-4-ONE NOVARTIS AG (CH) 1999-06-10 WO claimed
WO-1999027789-A1 FUNGICIDAL COMBINATIONS COMPRISING QUINAZOLINONE NOVARTIS AG (CH) 1999-06-10 WO claimed
EP-0907315-A1 PESTICIDAL COMPOSITIONS Novartis AG (CH) 1999-04-14 EP claimed
WO-1998000008-A1 PESTICIDAL COMPOSITIONS NOVARTIS AG (CH) 1998-01-08 WO claimed
EP-3352571-A1 NOVEL PLANT PROTECTING COMPOSITIONS AND USES THEREOF Flechsig Patent Company LLC (CH) 2018-08-01 EP disclosed
WO-2017050428-A1 NOVEL PLANT PROTECTING COMPOSITIONS AND USES THEREOF FLECHSIG PATENT COMPANY LLC (CH) 2017-03-30 WO disclosed
US-8765636-B2 Synergistic fungicidal active compound combinations containing a carboxamide, an azole, a second azole or a strobilurin BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-07-01 US disclosed
WO-1998055860-A1 PESTICIDE SCREENING SYSTEM NOVARTIS AG (CH) 1998-12-10 WO disclosed
WO-1998000009-A1 PESTICIDAL COMPOSITIONS NOVARTIS AG (CH) 1998-01-08 WO disclosed
WO-1998000008-A1 PESTICIDAL COMPOSITIONS NOVARTIS AG (CH) 1998-01-08 WO disclosed
WO-1997047606-A1 ARYLOXYACRYLIC ACID ESTERS BAYER AKTIENGESELLSCHAFT (DE) 1997-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035038-A1 Fungicidal combinations comprising thieno[2,3-d]pyrimidin-4-one MANBA, TPMT, TH HIF1A 4279/4885MEN1 281/4885KMT2A 1066/4885
US-20030065001-A1 Fungicidal combinations comprising quinazolinone MANBA, MAN2B1, GRM2 HIF1A 3690/4885MEN1 230/4885KMT2A 919/4885
US-20030130290-A1 Fungicidal combinations comprising thieno[2,3-d]pyrimidin-4-one MANBA, TPMT, DDT HIF1A 4216/4885MEN1 188/4885KMT2A 829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.