SCHEMBL2321633

SCHEMBL2321633

CO/N=C(\C(=O)OC)c1ccccc1CO/N=C(\C)c1cccc(C(F)(F)F)c1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.64
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
RXFP1 Q9HBX9 2/20 0.41
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297033 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL28465127 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL4448910 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL19148 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL29368184 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL9880011 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL29363702 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL7960472 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
SCHEMBL12635931 1.00 HIF1A (0.64) HIF1AMEN1KMT2APPARGPPARA
Hydrochloric Acid SCHEMBL17701148 0.99 HIF1A (0.63) HIF1AMEN1KMT2APPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 686 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200329703-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2020-10-22 US claimed
EP-3638032-A1 FUNGICIDAL COMPOSITIONS Syngenta Participations AG (CH) 2020-04-22 EP claimed
CN-110740644-A Fungicidal compositions 先正达参股股份有限公司 2020-01-31 CN claimed
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP claimed
WO-2018228896-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2018-12-20 WO claimed
EP-3010889-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-10-03 EP claimed
US-20170354150-A1 TERNARY FUNGICIDAL AND PESTICIDAL MIXTURES BAYER CROPSCIENCE AG (DE) 2017-12-14 US claimed
US-9642363-B2 N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG (DE) 2017-05-09 US claimed
EP-2997825-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND Bayer Intellectual Property GmbH (DE) 2016-03-23 EP claimed
US-20150313223-A1 TERNARY FUNGICIDAL MIXTURES BAYER CROPSCIENCE AG (DE) 2015-11-05 US claimed
CN-103635089-A Active compound combinations comprising a (thio)carboxamide derivative and a fungicidal compound BAYER IP GMBH 2014-03-12 CN claimed
EP-2699093-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND Bayer Intellectual Property GmbH (DE) 2014-02-26 EP claimed
US-20140038823-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGIDICAL COMPOUND BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2014-02-06 US claimed
EP-2515649-A2 ACTIVE COMPOUND COMBINATIONS Bayer Intellectual Property GmbH (DE) 2012-10-31 EP claimed
WO-2012143127-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND BAYER CROPSCIENCES AG (DE) 2012-10-26 WO claimed
EP-2398326-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE Bayer CropScience AG (DE) 2011-12-28 EP claimed
CN-102256489-A Active compound combinations BAYER CROPSCIENCE AG 2011-11-23 CN claimed
WO-2010094728-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2010-08-26 WO claimed
WO-2010069489-A1 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2010-06-24 WO claimed
EP-2011396-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200329703-A1 FUNGICIDAL COMPOSITIONS PFAS, NAT1, PAH HIF1A 4339/4885MEN1 613/4885KMT2A 1375/4885
US-20170354150-A1 TERNARY FUNGICIDAL AND PESTICIDAL MIXTURES DDT, CAT, CTRL HIF1A 4811/4885MEN1 827/4885KMT2A 2108/4885
US-20140038823-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGIDICAL COMPOUND AADAC, TUBA3C, NAT1 HIF1A 2730/4885MEN1 3136/4885KMT2A 1081/4885
US-20150313223-A1 TERNARY FUNGICIDAL MIXTURES CYP4X1, ERG28, CBR3 HIF1A 4627/4885MEN1 1186/4885KMT2A 2477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.