Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20521075 | 1.00 | CA1 (0.38) | CA1CA2CA7LMNAABCB1 | |
| SCHEMBL29705114 | 0.83 | LMNA (0.37) | LMNAKMT2ATDP1RXFP1ALDH1A1 | |
| SCHEMBL20520912 | 0.83 | LMNA (0.37) | LMNAKMT2ATDP1RXFP1ALDH1A1 | |
| SCHEMBL20521915 | 0.79 | LMNA (0.39) | LMNAKMT2APDE4BTDP1RXFP1 | |
| SCHEMBL29705124 | 0.79 | LMNA (0.39) | LMNAKMT2APDE4BTDP1RXFP1 | |
| SCHEMBL20521839 | 0.79 | LMNA (0.50) | LMNAKMT2ATDP1RXFP1MAPT | |
| SCHEMBL29705211 | 0.79 | LMNA (0.50) | LMNAKMT2ATDP1RXFP1MAPT | |
| SCHEMBL20521434 | 0.79 | LMNA (0.41) | LMNAKMT2ATDP1RXFP1MAPT | |
| SCHEMBL20521317 | 0.77 | LMNA (0.36) | LMNAKMT2ATDP1RXFP1MAPT | |
| SCHEMBL29705104 | 0.77 | LMNA (0.36) | LMNAKMT2ATDP1RXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110475777-B | Novel pyrido [2,3-b ] indole compounds for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | disclosed |