Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PARG | Q86W56 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27215181 | 1.00 | USP30 (0.42) | USP30DGAT1PRMT5WDR77AAK1 | |
| SCHEMBL2118034 | 0.91 | USP30 (0.43) | USP30DGAT1PRMT5WDR77AAK1 | |
| SCHEMBL13086540 | 0.84 | USP30 (0.39) | USP30DGAT1PRMT5WDR77AAK1 | |
| SCHEMBL3513272 | 0.80 | HSD17B10 (0.50) | DGAT1PRMT5WDR77AAK1FFAR1 | |
| SCHEMBL27215287 | 0.78 | HSD17B10 (0.39) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL29705389 | 0.78 | HSD17B10 (0.39) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL10223723 | 0.78 | USP30 (0.33) | USP30GABRG2GABRB3GABRA5 | |
| SCHEMBL27215192 | 0.77 | HSD17B10 (0.58) | USP30AAK1GABRG2GABRB3GABRA5 | |
| SCHEMBL29705392 | 0.77 | HSD17B10 (0.58) | USP30AAK1GABRG2GABRB3GABRA5 | |
| SCHEMBL12172282 | 0.75 | PRMT5 (0.43) | USP30DGAT1PRMT5WDR77AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |