Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27215192 | 1.00 | HSD17B10 (0.58) | HSD17B10HPGDHTTGABRG2GABRB3 | |
| SCHEMBL2117880 | 0.90 | HSD17B10 (0.47) | HSD17B10GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL29705389 | 0.86 | HSD17B10 (0.39) | HSD17B10HPGDHTTGABRG2GABRB3 | |
| SCHEMBL27215287 | 0.86 | HSD17B10 (0.39) | HSD17B10HPGDHTTGABRG2GABRB3 | |
| SCHEMBL15999448 | 0.83 | HSD17B10 (0.60) | HSD17B10HPGDHTTPDE4BLMNA | |
| SCHEMBL17471778 | 0.83 | ALDH1A1 (0.42) | HSD17B10HTTGABRG2GABRB3GABRA5 | |
| SCHEMBL16002440 | 0.83 | ALDH1A1 (0.42) | HSD17B10HTTGABRG2GABRB3GABRA5 | |
| SCHEMBL5418830 | 0.77 | CCNB2 (0.44) | HSD17B10HPGDGABRG2GABRB3GABRA5 | |
| SCHEMBL31710152 | 0.77 | LMNA (0.48) | HSD17B10HPGDGABRG2GABRB3GABRA5 | |
| SCHEMBL29705273 | 0.77 | USP30 (0.42) | HSD17B10HPGDHTTGABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |