Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27215189 | 1.00 | DGAT1 (0.36) | DGAT1NPC1MAPTPDE1B | |
| SCHEMBL27215119 | 0.85 | DGAT1 (0.36) | DGAT1NPC1PDE1B | |
| SCHEMBL29705264 | 0.85 | DGAT1 (0.36) | DGAT1NPC1PDE1B | |
| SCHEMBL24566116 | 0.84 | DGAT1 (0.37) | DGAT1PDE1B | |
| SCHEMBL30728763 | 0.83 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL27215308 | 0.83 | DGAT1 (0.36) | DGAT1NPC1 | |
| SCHEMBL27215085 | 0.83 | DGAT1 (0.38) | DGAT1NPC1 | |
| SCHEMBL29705290 | 0.83 | DGAT1 (0.38) | DGAT1NPC1 | |
| SCHEMBL29705326 | 0.83 | DGAT1 (0.36) | DGAT1NPC1 | |
| SCHEMBL3300284 | 0.82 | DGAT1 (0.39) | DGAT1NPC1PDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |