Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 12/20 | 0.38 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16793799 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL30897220 | 0.88 | CYP4F2 (0.43) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL19464040 | 0.84 | ALDH1A1 (0.46) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL30541744 | 0.84 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL25713504 | 0.84 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL25222791 | 0.84 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL30897247 | 0.84 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL15560133 | 0.84 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL22440514 | 0.84 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL22440498 | 0.83 | CYP4F2 (0.41) | CYP4F2CYP4A11ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |
| CN-108884050-B | Tetrahydroisoquinoline derivatives | UCB生物制药私人有限公司 | 2022-07-05 | — | — | CN | disclosed |