Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29705671 | 1.00 | OGG1 (0.42) | OGG1SLC6A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL23164153 | 1.00 | OGG1 (0.42) | OGG1SLC6A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL23164152 | 1.00 | OGG1 (0.42) | OGG1SLC6A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL23164171 | 1.00 | OGG1 (0.42) | OGG1SLC6A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL28749488 | 0.90 | OGG1 (0.44) | OGG1SLC6A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL29705659 | 0.90 | OGG1 (0.44) | OGG1SLC6A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL23164155 | 0.90 | OGG1 (0.44) | OGG1SLC6A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL23164157 | 0.90 | OGG1 (0.44) | OGG1SLC6A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL29705631 | 0.90 | OGG1 (0.44) | OGG1SLC6A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL23164258 | 0.75 | SLC6A4 (0.42) | OGG1SLC6A4KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |