Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.43 |
| ▸ | MDM4 | O15151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29692867 | 0.91 | CASP3 (0.48) | CASP3MDM2MDM4TP53PIN1 | |
| SCHEMBL29401938 | 0.87 | MDM4 (0.54) | CASP3MDM2MDM4TP53 | |
| SCHEMBL29908063 | 0.87 | MDM4 (0.54) | CASP3MDM2MDM4TP53 | |
| SCHEMBL1405811 | 0.87 | MDM4 (0.54) | CASP3MDM2MDM4TP53 | |
| SCHEMBL1405816 | 0.87 | MDM4 (0.54) | CASP3MDM2MDM4TP53 | |
| SCHEMBL1486208 | 0.87 | MDM4 (0.54) | CASP3MDM2MDM4TP53 | |
| SCHEMBL29353891 | 0.87 | MDM4 (0.54) | CASP3MDM2MDM4TP53 | |
| SCHEMBL29399772 | 0.87 | MDM4 (0.54) | CASP3MDM2MDM4TP53 | |
| SCHEMBL30241348 | 0.87 | PTPN1 (0.46) | MDM2MDM4TP53 | |
| Hydrochloric Acid SCHEMBL30912894 | 0.86 | MDM4 (0.53) | CASP3MDM2MDM4TP53TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024480-A | P-hydroxyphenylhydrazine compound phosphide and method for preparing Ang1-7 peptide compound assisted by same | 西北工业大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-116615436-A | Disulfide bond-containing polypeptide with serine protease activity inhibiting function, hybrid peptide derived from disulfide bond-containing polypeptide and application of disulfide bond-containing polypeptide | 中国医学科学院药物研究所 | 2023-08-18 | — | — | CN | disclosed |
| CN-114573686-A | Polypeptide containing disulfide bond and having serine protease activity inhibition function and application thereof | 中国医学科学院药物研究所 | 2022-06-03 | — | — | CN | disclosed |