SCHEMBL2970688

SCHEMBL2970688

CCCCc1ccccc1-c1ccc2c(c1Br)C=CC2C

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 2/20 0.32
CYSLTR1 Q9Y271 2/20 0.32
ELANE P08246 1/20 0.32
CTSG P08311 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
LIPG Q9Y5X9 1/20 0.31
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2971782 0.84 CYSLTR2 (0.31) CYSLTR2CYSLTR1ELANECTSGNR1H2
SCHEMBL2971771 0.81 CYSLTR2 (0.33) CYSLTR2CYSLTR1NR1H2NR1H3LIPG
SCHEMBL2965337 0.80 NR1H2 (0.32) NR1H2NR1H3LIPG
SCHEMBL2972325 0.80 NR1H2 (0.32) NR1H2NR1H3LIPG
SCHEMBL2970693 0.78 RARB (0.35)
SCHEMBL2966909 0.78 PPARA (0.31) CYSLTR2CYSLTR1NR1H2NR1H3
SCHEMBL2974318 0.76 ALDH1A1 (0.31)
SCHEMBL2972298 0.76 CYSLTR2 (0.31) CYSLTR2CYSLTR1NR1H2NR1H3LIPG
SCHEMBL2966213 0.76 CYSLTR2 (0.31) CYSLTR2CYSLTR1NR1H2NR1H3LIPG
SCHEMBL2973456 0.74 MAPT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 CYSLTR2 1369/4885CYSLTR1 1727/4885ELANE 829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.