Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.48 |
| ▸ | GRM5 | P41594 | 7/20 | 0.48 |
| ▸ | LIPC | P11150 | 1/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | QDPR | P09417 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174297 | 0.86 | NAMPT (0.56) | TLR7NAMPTGRM1GRM5PDK4 | |
| SCHEMBL6366609 | 0.86 | NAMPT (0.56) | TLR7NAMPTGRM1GRM5PDK4 | |
| SCHEMBL15184378 | 0.85 | NAMPT (0.53) | TLR7NAMPTGRM1GRM5PDK4 | |
| SCHEMBL29707442 | 0.84 | PDK4 (0.49) | TLR7NAMPTGRM1GRM5PDK4 | |
| SCHEMBL22957460 | 0.84 | PDK4 (0.49) | TLR7NAMPTGRM1GRM5PDK4 | |
| SCHEMBL24319593 | 0.84 | TLR7 (0.52) | TLR7NAMPTGRM1GRM5LIPC | |
| SCHEMBL29566866 | 0.84 | NAMPT (0.54) | TLR7NAMPTGRM1GRM5LIPC | |
| SCHEMBL15178435 | 0.84 | NAMPT (0.54) | TLR7NAMPTGRM1GRM5PDK4 | |
| SCHEMBL24309522 | 0.84 | NAMPT (0.54) | TLR7NAMPTGRM1GRM5LIPC | |
| SCHEMBL19703157 | 0.83 | NAMPT (0.53) | TLR7NAMPTGRM1GRM5PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414252-B1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | VALO HEALTH INC (US) | 2022-07-06 | — | — | EP | disclosed |