Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212226 | 1.00 | GPR119 (0.47) | GPR119ALDH1A1LMNAMAPTSMARCA2 | |
| SCHEMBL19212212 | 0.83 | KMT2A (0.37) | ALDH1A1LMNAMAPTMEN1CYP2C19 | |
| SCHEMBL22957295 | 0.82 | GPR119 (0.46) | GPR119ALDH1A1LMNAMAPTSMARCA2 | |
| SCHEMBL3922803 | 0.82 | GPR119 (0.48) | GPR119ALDH1A1LMNAMAPTEGLN2 | |
| SCHEMBL28931834 | 0.82 | NR1H2 (0.41) | GPR119 | |
| SCHEMBL25403559 | 0.81 | SMARCA2 (0.47) | GPR119ALDH1A1LMNAMAPTSMARCA2 | |
| SCHEMBL8436491 | 0.81 | GPR119 (0.49) | GPR119ALDH1A1LMNAMAPTSMARCA2 | |
| SCHEMBL22957297 | 0.80 | GPR119 (0.44) | GPR119ALDH1A1LMNAMAPTSMARCA2 | |
| SCHEMBL29707320 | 0.78 | MAPT (0.50) | GPR119ALDH1A1LMNAMAPTPDK2 | |
| SCHEMBL8415583 | 0.78 | GPR119 (0.49) | GPR119ALDH1A1LMNAMAPTSMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414252-B1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | VALO HEALTH INC (US) | 2022-07-06 | — | — | EP | disclosed |