Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 8/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17925972 | 0.84 | CSNK1D (0.41) | PRMT5WDR77NR1H2 | |
| SCHEMBL20159015 | 0.84 | CKS1B (0.49) | PRMT5WDR77NR1H2GPR119 | |
| SCHEMBL29707324 | 0.81 | MEN1 (0.41) | NR1H2 | |
| SCHEMBL17936835 | 0.79 | CYP3A4 (0.44) | PRMT5WDR77NR1H2 | |
| SCHEMBL17936827 | 0.77 | CSNK1D (0.44) | GPR119 | |
| SCHEMBL31605818 | 0.76 | NR1H2 (0.43) | NR1H2GPR119 | |
| SCHEMBL19632111 | 0.75 | NR1H2 (0.45) | NR1H2 | |
| SCHEMBL17936818 | 0.75 | CSNK1D (0.46) | GPR119CREBBP | |
| SCHEMBL26122508 | 0.74 | NR1H2 (0.41) | NR1H2GPR119CREBBP | |
| SCHEMBL25209603 | 0.74 | CSNK1E (0.47) | PRMT5WDR77GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414252-B1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | VALO HEALTH INC (US) | 2022-07-06 | — | — | EP | disclosed |