Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17665727 | 0.85 | MTNR1A (0.49) | NNMTMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL5760402 | 0.85 | KDM4E (0.47) | GPR183NNMTMEN1KMT2AKDM4E | |
| SCHEMBL15931171 | 0.84 | DAO (0.46) | ACACBFFAR1P4HTM | |
| SCHEMBL20665279 | 0.82 | CYP24A1 (0.49) | GPR183NNMTMEN1KMT2AKDM4E | |
| SCHEMBL4130730 | 0.81 | F2 (0.52) | NNMTSMN1; SMN2P4HTM | |
| SCHEMBL6307266 | 0.81 | CYP4F2 (0.56) | GPR183NNMTMEN1KMT2AKDM4E | |
| SCHEMBL29702259 | 0.81 | CYP4F2 (0.56) | GPR183NNMTMEN1KMT2AKDM4E | |
| SCHEMBL29886594 | 0.80 | P4HTM (0.58) | GPR183NNMTMEN1KMT2ANPC1 | |
| SCHEMBL6069860 | 0.80 | P4HTM (0.58) | GPR183NNMTMEN1KMT2ANPC1 | |
| SCHEMBL10982252 | 0.79 | CYP4F2 (0.50) | MTNR1AMTNR1BKMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805342-A | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and use thereof | 赛弗卢尔生命科学公司 | 2022-07-29 | — | — | CN | disclosed |