Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 5/20 | 0.45 |
| ▸ | TYMS | P04818 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23215660 | 1.00 | TYMP (0.45) | TYMPTYMSBRD4TMIGD3ADORA3 | |
| SCHEMBL29709101 | 1.00 | TYMP (0.45) | TYMPTYMSBRD4TMIGD3ADORA3 | |
| SCHEMBL23215200 | 1.00 | TYMP (0.45) | TYMPTYMSBRD4TMIGD3ADORA3 | |
| SCHEMBL3626996 | 0.94 | TYMP (0.46) | TYMPTYMS | |
| SCHEMBL3627000 | 0.94 | TYMP (0.46) | TYMPTYMS | |
| SCHEMBL26647641 | 0.93 | TYMP (0.45) | TYMPTYMS | |
| SCHEMBL26647525 | 0.93 | TYMP (0.45) | TYMPTYMS | |
| SCHEMBL30274693 | 0.92 | TYMP (0.43) | TYMPTYMSBRD4TMIGD3ADORA3 | |
| SCHEMBL30274889 | 0.92 | TYMP (0.43) | TYMPTYMSBRD4TMIGD3ADORA3 | |
| SCHEMBL30274796 | 0.92 | TYMP (0.44) | TYMPTYMSADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4404942-A2 | COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2024-07-31 | — | — | EP | disclosed |
| EP-4240849-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2023-09-13 | — | — | EP | disclosed |
| WO-2023049477-A2 | COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |
| EP-4022059-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2022-07-06 | — | — | EP | disclosed |