Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL17435796 | 0.88 | SLC1A2 (0.32) | ALDH1A1TSHRSLC1A2 | |
| SCHEMBL19766523 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL20995165 | 0.80 | — | — | |
| Trifluoroacetic Acid SCHEMBL20974146 | 0.80 | SLC1A2 (0.33) | ALDH1A1SLC1A2 | |
| Trifluoroacetic Acid SCHEMBL14738079 | 0.73 | ALDH1A1 (0.35) | ALDH1A1TSHRSLC1A2 | |
| Trifluoroacetic Acid SCHEMBL23358807 | 0.71 | MEN1 (0.32) | SLC1A2 | |
| Trifluoroacetic Acid SCHEMBL2455122 | 0.69 | ALDH1A1 (0.56) | ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL4250032 | 0.69 | FFAR3 (0.38) | ALDH1A1TSHRSLC1A2 | |
| Trifluoroacetic Acid SCHEMBL22553135 | 0.68 | — | — | |
| Trifluoroacetic Acid SCHEMBL31289849 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306079-B2 | 3-(5-amino-pyrazin-2-yl)-benzenesulfonamide derivatives and related compounds as PI3K-gamma kinase inhibitors | INCYTE CORPORATION (US) | 2022-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11306079-B2 | 3-(5-amino-pyrazin-2-yl)-benzenesulfonamide derivatives and related compounds as PI3K-gamma kinase inhibitors | PIK3CG, PIK3CD, PIK3CA | ALDH1A1 3432/4885TSHR 2418/4885SLC1A2 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.