Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790373 | 1.00 | HSD17B10 (0.48) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL31156796 | 0.94 | HSD17B10 (0.52) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL31286366 | 0.90 | HSD17B10 (0.54) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL30959837 | 0.86 | ALDH1A1 (0.48) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL1374119 | 0.86 | ALDH1A1 (0.48) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL2469870 | 0.84 | HSD17B10 (0.56) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL182202 | 0.82 | CYP1A2 (0.44) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL29391558 | 0.82 | ALDH1A1 (0.48) | HSD17B10ALDH1A1CYP1A2HPGDTSHR | |
| SCHEMBL5601608 | 0.82 | ALDH1A1 (0.48) | HSD17B10ALDH1A1CYP1A2HPGDTSHR | |
| SCHEMBL24488 | 0.82 | ALDH1A1 (0.48) | HSD17B10ALDH1A1CYP1A2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11355714-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11355714-B2 | Materials for organic electroluminescent devices | SLCO4C1, SLCO2A1, SLCO2B1 | HSD17B10 2582/4885ALDH1A1 1315/4885CYP1A2 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.