Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADM2 | Q7Z4H4 | 1/20 | 0.35 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20066152 | 1.00 | CALCA (0.42) | CALCAMEN1CYP2C9KMT2ACALCRL | |
| SCHEMBL30637892 | 0.91 | CALCA (0.41) | CALCACALCRLOTUD7BCYP1A2SMN1; SMN2 | |
| SCHEMBL16235885 | 0.90 | CALCA (0.46) | CALCACALCRLNPC1OTUD7BCYP1A2 | |
| SCHEMBL15999444 | 0.87 | CALCA (0.44) | CALCACALCRLNPC1RAMP1 | |
| SCHEMBL31456516 | 0.87 | CALCA (0.44) | CALCACALCRLNPC1OTUD7BCYP1A2 | |
| SCHEMBL15699749 | 0.87 | CALCA (0.44) | CALCACALCRLNPC1OTUD7BCYP1A2 | |
| SCHEMBL30087869 | 0.87 | CALCA (0.44) | CALCACALCRLNPC1RAMP1 | |
| SCHEMBL30087880 | 0.85 | CALCA (0.43) | CALCACALCRLRAMP1 | |
| SCHEMBL15999429 | 0.85 | CALCA (0.43) | CALCACALCRLRAMP1 | |
| SCHEMBL550356 | 0.84 | CALCA (0.50) | CALCACALCRLNPC1OTUD7BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834407-B2 | Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-12-05 | — | — | US | disclosed |
| CN-117003762-A | Piperidine formamide aza indane derivative, preparation method and application thereof | 熙源安健医药（上海）有限公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2023208124-A1 | PIPERIDINE CARBOXAMIDE AZAINDANE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | 熙源安健医药（上海）有限公司 | 2023-11-02 | — | — | WO | disclosed |
| US-20220213034-A1 | SUBSTITUTED CYCLOHEXANES AS MUSCARINIC M1 RECEPTOR AND/OR M4 RECEPTOR AGONISTS | NXERA PHARMA UK LIMITED (GB) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213034-A1 | SUBSTITUTED CYCLOHEXANES AS MUSCARINIC M1 RECEPTOR AND/OR M4 RECEPTOR AGONISTS | CHRM1, CHRM2, CHRM4 | CALCA 659/4885MEN1 791/4885CYP2C9 534/4885 |
| US-11834407-B2 | Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists | CHRM1, CHRM2, CHRM4 | CALCA 659/4885MEN1 791/4885CYP2C9 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.