Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 7/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 6/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16337053 | 1.00 | BTK (0.43) | BTKSNCALIPEGRM4CD274 | |
| SCHEMBL16320402 | 0.83 | POLB (0.40) | LIPE | |
| SCHEMBL21356707 | 0.82 | GRM4 (0.40) | BTKSNCAGRM4STK33CASP3 | |
| SCHEMBL16339752 | 0.82 | GRM5 (0.40) | LIPE | |
| SCHEMBL19897452 | 0.80 | LIPE (0.41) | LIPECD274 | |
| SCHEMBL23518565 | 0.79 | KMT2A (0.44) | LIPEGRM4 | |
| SCHEMBL21621000 | 0.78 | NPC1 (0.59) | BTKSNCAGRM4CASP3SENP8 | |
| SCHEMBL20293692 | 0.78 | LIPE (0.39) | BTKLIPE | |
| SCHEMBL16336876 | 0.78 | GRM4 (0.45) | BTKGRM4CASP3SENP8SENP7 | |
| SCHEMBL29709512 | 0.78 | GRM4 (0.45) | BTKGRM4CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008328-A1 | PRIMARY CARBOXAMIDES AS BTK INHIBITORS | AbbVie Inc. (US) | 2022-06-08 | — | — | EP | disclosed |