Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | HTT | P42858 | 2/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.84 |
| ▸ | NPC1 | O15118 | 1/20 | 0.84 |
| ▸ | MITF | O75030 | 1/20 | 0.84 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.84 |
| ▸ | RAB9A | P51151 | 1/20 | 0.84 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.84 |
| ▸ | RELA | Q04206 | 1/20 | 0.84 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290307 | 0.92 | LMNA (1.00) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL29709864 | 0.92 | LMNA (1.00) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL18034638 | 0.85 | LMNA (0.84) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL18034515 | 0.85 | LMNA (0.84) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL18034509 | 0.85 | LMNA (0.74) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL30496584 | 0.85 | LMNA (0.74) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL18034499 | 0.82 | LMNA (0.70) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL29709886 | 0.81 | LMNA (1.00) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL18034516 | 0.81 | LMNA (1.00) | LMNAHTTSMN1; SMN2NPC1MITF | |
| SCHEMBL18034494 | 0.81 | LMNA (0.74) | LMNAHTTSMN1; SMN2NPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107405330-B | Bamboo Bai ester compound with hypolipidemic activity, and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-08-01 | — | — | CN | disclosed |
| WO-2022143617-A1 | NAGILACTONE COMPOUND AND USE THEREOF IN PREPARATION OF ANTI-TUMOR DRUG | 中国科学院上海药物研究所 | 2022-07-07 | — | — | WO | disclosed |