Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA4 | P22748 | 2/20 | 0.60 |
| ▸ | CA6 | P23280 | 2/20 | 0.60 |
| ▸ | CA7 | P43166 | 2/20 | 0.60 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843116 | 0.83 | CA12 (0.72) | KMT2ACA12CA1CA4CA6 | |
| SCHEMBL5841502 | 0.81 | POLB (0.72) | KMT2ACA12CA1CA4CA6 | |
| SCHEMBL12245738 | 0.78 | KMT2A (0.59) | KMT2ACA12CA1CA4CA6 | |
| SCHEMBL21150842 | 0.77 | CA12 (0.68) | KMT2ACA12CA1CA4CA6 | |
| SCHEMBL5842380 | 0.77 | CA12 (0.68) | KMT2ACA12CA1CA4CA6 | |
| SCHEMBL5843350 | 0.76 | MAPT (0.72) | KMT2ACA12CA1CA4CA6 | |
| SCHEMBL5842225 | 0.76 | ALDH1A1 (0.77) | KMT2ACA12CA1CA4CA6 | |
| SCHEMBL2380600 | 0.76 | TSHR (0.52) | KMT2ACA12CA1CA4CA6 | |
| SCHEMBL12728561 | 0.75 | ALDH1A1 (0.62) | KMT2ACA12CA1CA4CA6 | |
| SCHEMBL5841136 | 0.75 | TP53 (0.68) | CA12CA1CA4CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003009-A1 | SECOND GENERATION INHIBITORS OF MITOCHONDRIAL PERMEABILITY TRANSITION PORE WITH IMPROVED PLASMA STABILITY | Oregon Health & Science University (US) | 2022-06-01 | — | — | EP | disclosed |