Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349022 | 1.00 | SIGMAR1 (0.68) | SIGMAR1 | |
| SCHEMBL4206840 | 0.92 | SIGMAR1 (0.80) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL2882074 | 0.90 | SIGMAR1 (0.78) | SIGMAR1 | |
| SCHEMBL2360705 | 0.86 | SIGMAR1 (0.73) | SIGMAR1 | |
| SCHEMBL19602179 | 0.83 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL467167 | 0.81 | SIGMAR1 (0.77) | SIGMAR1 | |
| SCHEMBL15963370 | 0.81 | SIGMAR1 (0.77) | SIGMAR1 | |
| SCHEMBL27987371 | 0.81 | SIGMAR1 (0.77) | SIGMAR1 | |
| SCHEMBL7437042 | 0.81 | SIGMAR1 (0.65) | SIGMAR1 | |
| SCHEMBL8010724 | 0.79 | SIGMAR1 (0.66) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776874-B2 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2010-08-17 | — | — | US | disclosed |
| EP-1756063-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1756063-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005110992-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2005-11-24 | — | — | WO | disclosed |