SCHEMBL29714859

SCHEMBL29714859

c1ccc2[nH]c(-c3n[nH]c4ccccc34)nc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 6/20 1.00
FLT1 P17948 6/20 1.00
PDPK1 O15530 4/20 0.71
ITK Q08881 2/20 0.71
CDK2 P24941 6/20 0.66
CHEK1 O14757 4/20 0.66
JAK2 O60674 2/20 0.66
TYK2 P29597 2/20 0.66
JAK3 P52333 2/20 0.66
CLK2 P49760 2/20 0.66
DYRK1A Q13627 2/20 0.66
KDR P35968 2/20 0.66
AURKA O14965 2/20 0.66
CDK1 P06493 2/20 0.66
AURKB Q96GD4 2/20 0.66
PLK4 O00444 1/20 0.66
CHUK O15111 1/20 0.66
ROCK2 O75116 1/20 0.66
MAP4K4 O95819 1/20 0.66
PAK4 O96013 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL311148 1.00 FGFR1 (1.00) FGFR1FLT1PDPK1ITKCDK2
SCHEMBL3532060 0.85 CHEK1 (0.79) FGFR1FLT1PDPK1CDK2CHEK1
SCHEMBL17583341 0.85 FGFR1 (0.73) FGFR1FLT1PDPK1ITKCDK2
SCHEMBL3533024 0.85 PDPK1 (0.73) FGFR1FLT1PDPK1ITKCDK2
SCHEMBL3536504 0.85 FGFR1 (0.73) FGFR1FLT1PDPK1ITKCDK2
SCHEMBL17556295 0.85 FGFR1 (0.73) FGFR1FLT1PDPK1ITKCDK2
SCHEMBL29381764 0.85 FGFR1 (0.73) FGFR1FLT1PDPK1ITKCDK2
SCHEMBL4918041 0.84 PDPK1 (0.76) FGFR1FLT1PDPK1ITKCDK2
SCHEMBL3541234 0.84 ITK (0.71) FGFR1FLT1PDPK1ITKCDK2
SCHEMBL5951751 0.84 PDPK1 (0.80) FGFR1FLT1PDPK1ITKCDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240270720-A1 INDAZOLE YL BENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2024-08-15 US claimed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
CN-114728132-B Injection system and method of use thereof 梅里特斯英国第二有限公司 2025-03-25 CN disclosed
CN-116600752-B Motorized injection system and method of use 梅里特斯英国第二有限公司 2025-01-14 CN disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
US-20240270720-A1 INDAZOLE YL BENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2024-08-15 US disclosed
US-20240270720-A1 INDAZOLE YL BENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2024-08-15 US disclosed
US-20240270720-A1 INDAZOLE YL BENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2024-08-15 US disclosed
CN-116600752-A Motorized injection system and method of use 梅里特斯英国第二有限公司 2023-08-15 CN disclosed
WO-2023287128-A1 INDAZOLE YL BENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF 한양대학교 에리카산학협력단 2023-01-19 WO disclosed
WO-2023287128-A1 INDAZOLE YL BENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF 한양대학교 에리카산학협력단 2023-01-19 WO disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
EP-4031214-A1 INJECTION SYSTEMS AND METHODS OF THEIR USE Bullseye Therapeutics, Inc. (US) 2022-07-27 EP disclosed
CN-114728132-A Injection system and method of use 梅拉格特克斯治疗学股份有限公司 2022-07-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240270720-A1 INDAZOLE YL BENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF FLT3, JAK2, JAK3 FGFR1 101/4885FLT1 752/4885PDPK1 597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.