Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 15/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26976746 | 1.00 | CHEK1 (0.51) | CHEK1IDO1TDO2CHEK2GPR119 | |
| SCHEMBL26976753 | 0.95 | CHEK1 (0.48) | CHEK1IDO1TDO2CHEK2GPR119 | |
| SCHEMBL29720802 | 0.95 | CHEK1 (0.48) | CHEK1IDO1TDO2CHEK2GPR119 | |
| SCHEMBL26976965 | 0.88 | CHEK1 (0.47) | CHEK1IDO1TDO2CHEK2GPR119 | |
| SCHEMBL26976860 | 0.88 | CHEK1 (0.55) | CHEK1IDO1TDO2CHEK2GPR119 | |
| SCHEMBL26976787 | 0.87 | CHEK1 (0.53) | CHEK1CHEK2GPR119 | |
| SCHEMBL26976771 | 0.86 | CHEK1 (0.52) | CHEK1IDO1TDO2CHEK2GPR119 | |
| SCHEMBL26976670 | 0.85 | CHEK1 (0.57) | CHEK1CHEK2GPR119 | |
| SCHEMBL26976985 | 0.85 | CHEK1 (0.52) | CHEK1CHEK2GPR119 | |
| SCHEMBL26976725 | 0.85 | CHEK1 (0.45) | CHEK1IDO1TDO2CHEK2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4298095-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | Sperogenix Therapeutics Limited (HK) | 2024-01-03 | — | — | EP | disclosed |
| WO-2022162606-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | SPEROGENIX THERAPEUTICS LIMITED (CN) | 2022-08-04 | — | — | WO | disclosed |