Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 10/20 | 0.58 |
| ▸ | EGFR | P00533 | 6/20 | 0.58 |
| ▸ | ABL1 | P00519 | 5/20 | 0.58 |
| ▸ | ABL2 | P42684 | 5/20 | 0.58 |
| ▸ | RET | P07949 | 1/20 | 0.57 |
| ▸ | KIF5B | P33176 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 6/20 | 0.56 |
| ▸ | HCK | P08631 | 2/20 | 0.56 |
| ▸ | FLT3 | P36888 | 2/20 | 0.56 |
| ▸ | BTK | Q06187 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344421 | 1.00 | SRC (0.58) | SRCEGFRABL1ABL2RET | |
| SCHEMBL28667953 | 0.83 | SRC (0.79) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL20351777 | 0.83 | SRC (0.66) | SRCEGFRABL1ABL2RET | |
| SCHEMBL20351628 | 0.82 | SRC (0.80) | SRCEGFRABL1ABL2KDR | |
| SCHEMBL29720961 | 0.82 | ADK (0.47) | SRCEGFRABL1RETKIF5B | |
| SCHEMBL28344423 | 0.82 | ADK (0.47) | SRCEGFRABL1RETKIF5B | |
| SCHEMBL13020339 | 0.81 | RET (0.66) | SRCEGFRABL1ABL2RET | |
| SCHEMBL18044541 | 0.80 | SRC (0.81) | SRCEGFRABL1ABL2RET | |
| SCHEMBL20351767 | 0.80 | SRC (0.88) | SRCEGFRABL1ABL2BTK | |
| SCHEMBL29720934 | 0.80 | BTK (0.57) | SRCEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627796-B | Nitrogenous heterocyclic derivative and application thereof in medicine | 北京越之康泰生物医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |