Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.45 |
| ▸ | TNKS | O95271 | 5/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30160881 | 0.83 | CRBN (0.51) | KDM4EALDH1A1HPGDCRBNDDB1 | |
| SCHEMBL29721390 | 0.80 | TNKS (0.46) | KDM4EALDH1A1HPGDCRBNDDB1 | |
| SCHEMBL31218916 | 0.80 | TNKS (0.63) | KDM4EALDH1A1HPGDCRBNDDB1 | |
| SCHEMBL30674307 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1HPGDCRBNDDB1 | |
| SCHEMBL31653832 | 0.76 | KEAP1 (0.43) | KDM4EALDH1A1HPGDKEAP1P2RX7 | |
| SCHEMBL317703 | 0.76 | KEAP1 (0.43) | KDM4EALDH1A1HPGDKEAP1P2RX7 | |
| SCHEMBL29606630 | 0.76 | CRBN (0.49) | KDM4EALDH1A1HPGDCRBNDDB1 | |
| SCHEMBL21409229 | 0.76 | CRBN (0.49) | KDM4EALDH1A1HPGDCRBNDDB1 | |
| SCHEMBL23983302 | 0.75 | CRBN (0.63) | HPGDCRBNDDB1PARP1P2RX7 | |
| SCHEMBL21409269 | 0.75 | CRBN (0.45) | KDM4EALDH1A1HPGDCRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114641473-A | BRD9 bifunctional degradation agent and use method thereof | 诺华股份有限公司 | 2022-06-17 | — | — | CN | disclosed |