Pyrazine

Pyrazine

SCHEMBL2972134

CCCCCN.[Ru].c1cnccn1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 9/20 0.60
TSHR P16473 2/20 0.60
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
ALDH1A1 P00352 1/20 0.60
EPHX1 P07099 1/20 0.60
HRH1 P35367 2/20 0.41
NFKB1 P19838 1/20 0.37
HTR2A P28223 1/20 0.37
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrazine SCHEMBL28063045 0.97 DNM1 (0.63) DNM1TSHRMEN1KMT2AALDH1A1
Pyridine SCHEMBL3059946 0.88 DNM1 (0.52) DNM1TSHRMEN1KMT2AALDH1A1
Pyridine SCHEMBL27501548 0.85 DNM1 (0.55) DNM1TSHRMEN1KMT2AALDH1A1
Pentadecylamine SCHEMBL27543576 0.83 DNM1 (0.59) DNM1TSHRMEN1KMT2AALDH1A1
Dodecylamine SCHEMBL4454392 0.83 DNM1 (0.59) DNM1TSHRMEN1KMT2AALDH1A1
Hexadecylamine SCHEMBL27881439 0.83 DNM1 (0.59) DNM1TSHRMEN1KMT2AALDH1A1
Tetradecylamine SCHEMBL28651431 0.83 DNM1 (0.59) DNM1TSHRMEN1KMT2AALDH1A1
Pyridine SCHEMBL27971866 0.83 DNM1 (0.59) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL6942619 0.83
Dodecylamine SCHEMBL25413601 0.81 DNM1 (0.61) DNM1TSHRMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620570-B1 ELECTROCHEMICAL METHOD TO MEASURE DNA ATTACHMENT TO AN ELECTRODE SURFACE IN THE PRESENCE OF MOLECULAR OXYGEN GENEOHM SCIENCES (US) 2010-09-15 EP claimed