Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 5/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | CD38 | P28907 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23170105 | 1.00 | NUDT1 (0.54) | NUDT1TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL23147850 | 1.00 | NUDT1 (0.54) | NUDT1TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL23147696 | 0.88 | NUDT1 (0.54) | NUDT1NPC1RAB9ASETD2TBK1 | |
| SCHEMBL23147244 | 0.87 | NUDT1 (0.53) | NUDT1SETD2TBK1CD38MLLT1 | |
| SCHEMBL29721662 | 0.87 | NUDT1 (0.53) | NUDT1SETD2TBK1CD38MLLT1 | |
| SCHEMBL29721613 | 0.87 | NUDT1 (0.55) | NUDT1TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL23148092 | 0.87 | NUDT1 (0.55) | NUDT1TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL23170280 | 0.87 | NUDT1 (0.55) | NUDT1TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL23147845 | 0.86 | NUDT1 (0.50) | NUDT1SETD2TBK1CD38MLLT1 | |
| SCHEMBL23147753 | 0.86 | NUDT1 (0.50) | NUDT1TAS1R3TAS1R1TAS1R2SETD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | claimed |
| EP-4034108-A1 | AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | The Global Alliance for TB Drug Development, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |