Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 7/20 | 0.55 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23147892 | 1.00 | NUDT1 (0.55) | NUDT1TBK1SMYD3PLA2G7MAPK14 | |
| SCHEMBL23147750 | 0.89 | NUDT1 (0.55) | NUDT1TBK1SMYD3MLLT1SYK | |
| SCHEMBL29722076 | 0.89 | NUDT1 (0.55) | NUDT1TBK1SMYD3MLLT1SYK | |
| SCHEMBL29721532 | 0.88 | NUDT1 (0.59) | NUDT1TBK1SMYD3PLA2G7MAPK14 | |
| SCHEMBL23147818 | 0.88 | NUDT1 (0.59) | NUDT1TBK1SMYD3PLA2G7MAPK14 | |
| SCHEMBL23147481 | 0.87 | NUDT1 (0.51) | NUDT1TBK1PLA2G7MLLT1SETD2 | |
| SCHEMBL29721638 | 0.87 | NUDT1 (0.51) | NUDT1TBK1PLA2G7MLLT1SETD2 | |
| SCHEMBL23147244 | 0.82 | NUDT1 (0.53) | NUDT1TBK1SMYD3MLLT1SETD2 | |
| SCHEMBL29721662 | 0.82 | NUDT1 (0.53) | NUDT1TBK1SMYD3MLLT1SETD2 | |
| SCHEMBL23169934 | 0.78 | NUDT1 (0.46) | NUDT1TBK1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | claimed |
| EP-4034108-A1 | AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | The Global Alliance for TB Drug Development, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |