Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932828 | 0.85 | KDM4E (0.61) | KDM4EKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL9081166 | 0.85 | KDM4E (0.61) | KDM4EKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL12467591 | 0.81 | KDM4E (0.56) | KDM4EKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL29357675 | 0.79 | KDM4E (0.76) | KDM4EKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL70765 | 0.79 | KDM4E (0.76) | KDM4EKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL498897 | 0.79 | KDM4E (1.00) | KDM4EKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL16139778 | 0.79 | KDM4E (0.62) | KDM4EKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL5014392 | 0.77 | ALDH1A1 (0.59) | KDM4EKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL143651 | 0.77 | KDM4E (0.73) | KDM4EKMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL29355234 | 0.77 | KDM4E (0.73) | KDM4EKMT2AMEN1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119570160-A | High-impact material prepared from recycled polypropylene and preparation method thereof | 肇庆市合亚科技有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119570160-B | High-impact material prepared from recycled polypropylene and preparation method thereof | 肇庆市合亚科技有限公司 | 2025-08-22 | — | — | CN | disclosed |
| CN-119570160-A | High-impact material prepared from recycled polypropylene and preparation method thereof | 肇庆市合亚科技有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119570160-A | High-impact material prepared from recycled polypropylene and preparation method thereof | 肇庆市合亚科技有限公司 | 2025-03-07 | — | — | CN | disclosed |
| US-8283367-B2 | Proteasome inhibitors and methods of using the same | CEPHALON, INC. (US) | 2012-10-09 | — | — | US | disclosed |
| EP-1846424-B1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2010-01-27 | — | — | EP | disclosed |
| US-20090075936-A1 | Proteasome inhibitors and methods of using the same | CEPHALON, INC. (US) | 2009-03-19 | — | — | US | disclosed |
| US-7468383-B2 | Proteasome inhibitors and methods of using the same | CEPHALON, INC. (US) | 2008-12-23 | — | — | US | disclosed |
| CN-101120006-A | Proteasome inhibitors and methods of using the same | CEPHALON INC (US) | 2008-02-06 | — | — | CN | disclosed |
| EP-1846424-A1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON, INC. (US) | 2007-10-24 | — | — | EP | disclosed |
| US-20060189806-A1 | Proteasome inhibitors and methods of using the same | CEPHALON, INC. (US) | 2006-08-24 | — | — | US | disclosed |
| WO-2006086600-A1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON, INC. (US) | 2006-08-17 | — | — | WO | disclosed |
| WO-1996022292-A1 | TRICYCLIC VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189806-A1 | Proteasome inhibitors and methods of using the same | PSMB11, PSMB5, PSMB6 | KDM4E 1640/4885KMT2A 2205/4885MEN1 2309/4885 |
| US-20090075936-A1 | Proteasome inhibitors and methods of using the same | PSMB11, PSMB5, PSMB6 | KDM4E 1640/4885KMT2A 2205/4885MEN1 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.