Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 4/20 | 0.54 |
| ▸ | PLA2G7 | Q13093 | 8/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148159 | 1.00 | NUDT1 (0.54) | NUDT1PLA2G7HTTMLLT1MEN1 | |
| SCHEMBL29721944 | 0.86 | NUDT1 (0.50) | NUDT1TBK1 | |
| SCHEMBL23147659 | 0.86 | NUDT1 (0.50) | NUDT1TBK1 | |
| SCHEMBL29721532 | 0.85 | NUDT1 (0.59) | NUDT1PLA2G7MLLT1KMT2ATBK1 | |
| SCHEMBL23147942 | 0.85 | NUDT1 (0.54) | NUDT1PLA2G7MLLT1 | |
| SCHEMBL23147696 | 0.85 | NUDT1 (0.54) | NUDT1PLA2G7MLLT1TBK1 | |
| SCHEMBL23147818 | 0.85 | NUDT1 (0.59) | NUDT1PLA2G7MLLT1KMT2ATBK1 | |
| SCHEMBL23147804 | 0.84 | NUDT1 (0.53) | NUDT1PLA2G7MLLT1TBK1 | |
| SCHEMBL23147730 | 0.83 | NUDT1 (0.52) | NUDT1PLA2G7MLLT1 | |
| SCHEMBL23147945 | 0.82 | NUDT1 (0.51) | NUDT1PLA2G7MLLT1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | claimed |
| EP-4034108-A1 | AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | The Global Alliance for TB Drug Development, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |