Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 5/20 | 0.54 |
| ▸ | CCNK | O75909 | 3/20 | 0.51 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 6/20 | 0.38 |
| ▸ | CDK8 | P49336 | 6/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29722004 | 0.85 | IDO1 (0.49) | NUDT1CCNKCDK12SNCA | |
| SCHEMBL3008612 | 0.85 | IDO1 (0.49) | NUDT1CCNKCDK12SNCA | |
| SCHEMBL23148011 | 0.84 | NUDT1 (0.42) | NUDT1CCNKCDK12SNCACCNT1 | |
| SCHEMBL29721909 | 0.84 | NUDT1 (0.42) | NUDT1CCNKCDK12SNCACCNT1 | |
| SCHEMBL30731013 | 0.81 | NUDT1 (0.61) | NUDT1CCNKCDK12CCNCCDK8 | |
| SCHEMBL20839895 | 0.81 | NUDT1 (0.61) | NUDT1CCNKCDK12CCNCCDK8 | |
| SCHEMBL29721793 | 0.80 | NUDT1 (0.51) | NUDT1CCNKCDK12CCNCCDK8 | |
| SCHEMBL29722000 | 0.77 | CCNK (0.42) | NUDT1CCNKCDK12CCNCCDK8 | |
| SCHEMBL28810609 | 0.77 | CCNK (0.42) | NUDT1CCNKCDK12CCNCCDK8 | |
| SCHEMBL29063177 | 0.74 | IDO1 (0.54) | NUDT1CCNCCDK8MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |